This street that leads to the castle (the clue is in the name) is lined with tower-houses, palazzi (Palazzo dei Priori houses the Sacred Art Museum - Museo Civico e d'Arte Sacre -, which has many 16C and 17C paintings by the Florentine and Sienese Schools), the Teatro dei Varii, founded in the 18C in the former Hospital of the Holy Spirit. Arnolfo di Cambio is said to have been born in the last tower-house on the street around 1245; the name may not familiar, but he was none other than the architect behind Florence's Duomo.